Identify a number of empty storefronts in both downtown and 13th Avenue areas and create 2-3 small business incubators. There could be an agricultural products incubator (to launch products related to things grown/raised in the area--which could be sold in the smaller markets and larger stores in the area), a small manufacturing incubator, etc. This would create new businesses in places near established businesses, and locate services near fledgling businesses.

Detroit is in the process of building an artist/artisan incubator. It intersects art and commerce in interesting ways: http://71pop.com/